The German-Arab Knowledge Transfer Colloquium hosted by the Centre for Logistics and Traffic (ZLV) of the University Duisburg-Essen (UDE) has united professors and PhD students from the MENA Region and the UDE-network during a ten-day programme leading through urban challenges in the sectors of “Water, Energy and Food” and the big task of conceptually combining their functional domains, referring to the concept of “Water-Energy-Food Supply Nexus”. The colloquium, held in December 2017 and funded by the DAAD with means of the Federal Foreign Office, challenged the German-Arab group of experts to detect the biggest obstacles against and develop first steps towards a sustainable W-E-F Nexus in the MENA Region in terms of knowledge, practice and decision making. Ever since the event, several dialogues have been initiated between Arab participants, the UDE and external experts continuing the overarching objective.